What type of feedback promotes homeostasis
The muscle contractions of shivering release heat while using up ATP. The brain triggers the thyroid gland in the endocrine system to release thyroid hormone, which increases metabolic activity and heat production in cells throughout the body. The brain also signals the adrenal glands to release epinephrine adrenaline , a hormone that causes the breakdown of glycogen into glucose, which can be used as an energy source.
The breakdown of glycogen into glucose also results in increased metabolism and heat production. A deviation from the normal range results in more change, and the system moves farther away from the normal range. Positive feedback in the body is normal only when there is a definite end point. Childbirth at full term is an example of a situation in which the maintenance of the existing body state is not desired. The events of childbirth, once begun, must progress rapidly to a conclusion or the life of the mother and the baby are at risk.
The extreme muscular work of labor and delivery are the result of a positive feedback system Figure 1. The first contractions of labor the stimulus push the baby toward the cervix the lowest part of the uterus.
The cervix contains stretch-sensitive nerve cells that monitor the degree of stretching the sensors. These nerve cells send messages to the brain, which in turn causes the pituitary gland at the base of the brain to release the hormone oxytocin into the bloodstream. Oxytocin causes stronger contractions of the smooth muscles in of the uterus the effectors , pushing the baby further down the birth canal.
This causes even greater stretching of the cervix. The cycle of stretching, oxytocin release, and increasingly more forceful contractions stops only when the baby is born. At this point, the stretching of the cervix halts, stopping the release of oxytocin. A second example of positive feedback centers on reversing extreme damage to the body. Following a penetrating wound, the most immediate threat is excessive blood loss.
Less blood circulating means reduced blood pressure and reduced perfusion penetration of blood to the brain and other vital organs. If perfusion is severely reduced, vital organs will shut down and the person will die. The body responds to this potential catastrophe by releasing substances in the injured blood vessel wall that begin the process of blood clotting.
As each step of clotting occurs, it stimulates the release of more clotting substances. This accelerates the processes of clotting and sealing off the damaged area. Clotting is contained in a local area based on the tightly controlled availability of clotting proteins. This is an adaptive, life-saving cascade of events. Homeostasis is the activity of cells throughout the body to maintain the physiological state within a narrow range that is compatible with life.
Homeostasis is regulated by negative feedback loops and, much less frequently, by positive feedback loops. Both have the same components of a stimulus, sensor, control center, and effector; however, negative feedback loops work to prevent an excessive response to the stimulus, whereas positive feedback loops intensify the response until an end point is reached. Identify the four components of a negative feedback loop and explain what would happen if secretion of a body chemical controlled by a negative feedback system became too great.
The four components of a negative feedback loop are: stimulus, sensor, control center, and effector. If too great a quantity of the chemical were excreted, sensors would activate a control center, which would in turn activate an effector.
In this case, the effector the secreting cells would be adjusted downward. What regulatory processes would your body use if you were trapped by a blizzard in an unheated, uninsulated cabin in the woods? This would reduce blood flow to your skin, and shunt blood returning from your limbs away from the digits and into a network of deep veins. We will discuss homeostasis in every subsequent system. Many aspects of the body are in a constant state of change—the volume and location of blood flow, the rate at which substances are exchanged between cells and the environment, and the rate at which cells are growing and dividing, are all examples.
For example, blood flow will increase to a tissue when that tissue becomes more active. This ensures that the tissue will have enough oxygen to support its higher level of metabolism. Maintaining internal conditions in the body is called homeostasis from homeo-, meaning similar, and stasis, meaning standing still.
But if you think about anatomy and physiology, even maintaining the body at rest requires a lot of internal activity. Your brain is constantly receiving information about the internal and external environment, and incorporating that information into responses that you may not even be aware of, such as slight changes in heart rate, breathing pattern, activity of certain muscle groups, eye movement, etc.
Any of these actions that help maintain the internal environment contribute to homeostasis. We can consider the maintenance of homeostasis on a number of different levels.
For example, consider what happens when you exercise, which can represent challenges to various body systems. Yet instead of these challenges damaging your body, our systems adapt to the situation.
At the whole-body level, you notice some specific changes: your breathing and heart rate increase, your skin may flush, and you may sweat. If you continue to exercise, you may feel thirsty. These effects are all the result of your body trying to maintain conditions suitable for normal function:. Feedback loop is defined as a system used to control the level of a variable in which there is an identifiable receptor sensor , control center integrator or comparator , effectors, and methods of communication.
Terminology in this area is often inconsistent. For example, there are cases where components of a feedback loop are not easily identifiable, but variables are maintained in a range.
Such situations are still examples of homeostasis and are sometimes described as a feedback cycle instead of a feedback loop. Feedback Cycle is defined as any situation in which a variable is regulated and the level of the variable impacts the direction in which the variable changes i. With this terminology in mind, homeostasis then can be described as the totality of the feedback loops and feedback cycles that the body incorporates to maintain a suitable functioning status.
Air conditioning is a technological system that can be described in terms of a feedback loop. The thermostat senses the temperature, an electronic interface compares the temperature against a set point the temperature that you want it to be.
If the temperature matches or is cooler, then nothing happens. If the temperature is too hot, then the electronic interface triggers the air-conditioning unit to turn on. Once the temperature is lowered sufficiently to reach the set point, the electronic interface shuts the air-conditioning unit off.
For this example, identify the steps of the feedback loop. Cruise control is another technological feedback system. The idea of cruise control is to maintain a constant speed in your car. If the speed is too slow, the interface stimulates the engine; if the speed is too fast, the interface reduces the power to the tires.
Remember that homeostasis is the maintenance of a relatively stable internal environment. When a stimulus, or change in the environment, is present, feedback loops respond to keep systems functioning near a set point, or ideal level.
Feedback is a situation when the output or response of a loop impacts or influences the input or stimulus. Positive feedback loops are inherently unstable systems. Because a change in an input causes responses that produce continued changes in the same direction, positive feedback loops can lead to runaway conditions.
The term positive feedback is typically used as long as a variable has an ability to amplify itself, even if the components of a loop receptor, control center and effector are not easily identifiable. In most cases, positive feedback is harmful, but there are a few instances where positive feedback, when used in limited fashion, contributes to normal function. For example, during blood clotting, a cascade of enzymatic proteins activates each other, leading to the formation of a fibrin clot that prevents blood loss.
One of the enzymes in the pathway, called thrombin, not only acts on the next protein in the pathway but also has an ability to activate a protein that preceded it in the cascade. This latter step leads to a positive feedback cycle, where an increase in thrombin leads to further increases in thrombin.
But if we just consider the effects of thrombin on itself, it is considered a positive feedback cycle. Although some may consider this a positive feedback loop, such terminology is not universally accepted.
Negative feedback loops are inherently stable systems. Negative feedback loops, in conjunction with the various stimuli that can affect a variable, typically produce a condition in which the variable oscillates around the set point.
For example, negative feedback loops involving insulin and glucagon help to keep blood glucose levels within a narrow concentration range.
If glucose levels get too high, the body releases insulin into the bloodstream. In a positive feedback mechanism, the output of the system stimulates the system in such a way as to further increase the output. As noted, there are some physiologic processes that are commonly considered to be positive feedback, although they may not all have identifiable components of a feedback loop.
In these cases, the positive feedback loop always ends with counter-signaling that suppresses the original stimulus. A good example of positive feedback involves the amplification of labor contractions. The contractions are initiated as the baby moves into position, stretching the cervix beyond its normal position. The feedback increases the strength and frequency of the contractions until the baby is born.
After birth, the stretching stops and the loop is interrupted. Another example of positive feedback occurs in lactation, during which a mother produces milk for her infant. During pregnancy, levels of the hormone prolactin increase.
Prolactin normally stimulates milk production, but during pregnancy, progesterone inhibits milk production. At birth, when the placenta is released from the uterus, progesterone levels drop. As a result, milk production surges. As the baby feeds, its suckling stimulates the breast, promoting further release of prolactin, resulting in yet more milk production. This positive feedback ensures the baby has sufficient milk during feeding.
The above provide examples of beneficial positive feedback mechanisms. However, in many instances, positive feedback can be potentially damaging to life processes.
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